Skip to content

Effect of Coffee on Eye

The Effect of Caffeine on Choroidal Thickness, Vascularization index, and Anterior Segment Parameters of the Eye in healthy population

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231031059914N1
Enrollment
50
Registered
2023-11-13
Start date
2023-12-06
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Choroidal thickness changes. Condition 2: Changes in anterior segment factors. Condition 3: Changes in choroidal vascular index.

Interventions

Intervention 1: Intervention group: These people are given caffeinated coffee. Intervention 2: Control group: These people are given decaffeinated coffee.

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Ocular health in normal examination Not using hard contact lenses in the last month Not using soft contact lenses in the last two weeks Personal consent to participate in the research project Not consuming coffee at least 4 hours before attending the program No smoking Not drinking coffee or any caffeinated drinks during the test

Exclusion criteria

Exclusion criteria: History of systemic and ophthalmic disease People with cardiac arrhythmia History of hypertension, diabetes, glaucoma, uveitis Pregnancy and breastfeeding Taking medications that affect posterior and anterior segment of the eye History of eye surgery

Design outcomes

Primary

MeasureTime frame
Choroidal vascularity index. Timepoint: Before intervention and 1, 2, 3, and 4 hours after intervention. Method of measurement: Posterior and anterior optical coherence tomography.;Angle-opening distance. Timepoint: Before intervention and 1, 2, 3, and 4 hours after intervention. Method of measurement: Posterior and anterior optical coherence tomography.;Trabecular iris angle. Timepoint: Before intervention and 1, 2, 3, and 4 hours after intervention. Method of measurement: Posterior and anterior optical coherence tomography.;Trabecular iris space area. Timepoint: Before intervention and 1, 2, 3, and 4 hours after intervention. Method of measurement: Posterior and anterior optical coherence tomography.;Anterior chamber depth. Timepoint: Before intervention and 1, 2, 3, and 4 hours after intervention. Method of measurement: Posterior and anterior optical coherence tomography.;Choroidal thickness. Timepoint: Before intervention and 1, 2, 3, and 4 hours after intervention. Method of measurement: Posterior and anterior optical coherence tomography.;Corneal thickness. Timepoint: Before intervention and 1, 2, 3, and 4 hours after intervention. Method of measurement: Posterior and anterior optical coherence tomography.;Choroidal luminal thickness. Timepoint: Before intervention and 1, 2, 3, and 4 hours after intervention. Method of measurement: Posterior and anterior optical coherence tomography.;Choroidal stromal thickness. Timepoint: Before intervention and 1, 2, 3, and 4 hours after intervention. Method of measurement: Posterior and anterior optical coherence tomography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactIman Varshovi-Jaghargh

Mashhad University of Medical Sciences

I.Varshovi@gmail.com+98 51 3881 8761

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026