Medical (legal) abortion. (Induced) termination of pregnancy with other and unspecified complications
Conditions
Interventions
Intervention 1: Control group: Control group patients are treated with vaginal misoprostol according to the latest FIGO protocol published in 2023, during which, for pregnancies less than 13 weeks old
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Consent to participation Aged 18 to 45 years Confirmed gestational age below 19 weeks based on the Iranian Legal Medicine Organization documentation History of at least one previous cesarean sections Confirmed diagnosis of a fetal structural or chromosomal anomaly with an indication for legal abortion Detected fetal heart activity in the last ultrasonographic examination Having an Iranian Legal Medicine Organization approval for the legal abortion with a certain date
Exclusion criteria
Exclusion criteria: Refusal to participation Confirmed gestational age over 19 weeks based on the Iranian Legal Medicine Organization documentation No history of prior cesarean sections Not having a confirmed diagnosis of fetal structural or chromosomal anomaly Not having an Iranian Legal Medicine Organization approval for the legal abortion with a certain date No fetal heart activity detected in the last ultrasonographic examination Presence of vaginal bleeding in the mother Chronic abdominal pain in the mother Diagnosis of acute abdomen in the mother Presence abdominal cramps in the mother before the initiation of the treatment Diagnosis of premature rupture of the amniotic membrane
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete (successful) abortion: complete removal of the placenta and fetus from the uterus, proven by an empty uterine cavity in sonographic examinations. Timepoint: After prescribing the treatment, all patients in the two study groups will undergo transvaginal ultrasound within 24 hours after the removal of the pregnancy product, and if the pregnancy remains less than 30 mm are observed, they will be discharged. Patients who have remnants of more than 30 mm will receive misoprostol and again within 24 hours after the removal of the pregnancy product, they will undergo ultrasound to check for remnants of pregnancy and placental retention. Method of measurement: Ultrasonographic transvaginal examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Golshahi
Tehran University of Medical Sciences
Outcome results
None listed