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Comparison of the effect of venesection (Fasd)

Comparison of the effect of venesection (Fasd) with phlebotomy on serum ferritin changes in patients with non-alcoholic fatty liver disease and hyperferritinemia: a randomized clinical trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231025059862N2
Enrollment
48
Registered
2024-07-10
Start date
2024-06-29
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fatty Liver. Fatty (change of) liver, Nonalcoholic fatty liver disease [NAFLD]

Interventions

Intervention 1: Intervention group: In the phlebotomy group, venous blood was injected from the median cubital vein of the right upper limb by a syringe head with a Pharmed company bag in the amount o

Sponsors

Gorgan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 18 to 60 years - ferritin = 150 ng/dl for women and ferritin = 200 ng/dl for men - ALT > 41u/l - fatty liver grade 2 or higher in ultrasound or definitive diagnosis of NAFLD in fibroscan

Exclusion criteria

Exclusion criteria: Faint's history during blood sampling, diabetes, severe cardiovascular disease, anemia (hemoglobin number less than 13 in men and less than 12 in women), presence of pregnancy and breastfeeding, and participation in the clinical study of other liver diseases in the previous 2 months From entering the present study

Design outcomes

Primary

MeasureTime frame
Decreased serum ferritin. Timepoint: After 4 weeks. Method of measurement: Blood test.

Secondary

MeasureTime frame
Low of blood pressure. Timepoint: After 4 weeks. Method of measurement: Mercury pressure gauge.;Decrease in the amount of ALT enzyme. Timepoint: After 4 weeks. Method of measurement: Blood test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Zarvandi

Gorgan University of Medical Sciences

leg_med_ny@yahoo.com+98 915 551 2909

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026