Comparison of the effects of Normal-saline and Half-saline in the treatment of children with diabetic ketoacidosis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20231025059849N1

Enrollment

Registered

2024-01-12

Start date

2024-03-20

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabet mellitus-DKA. Diabetes mellitus due to underlying condition

Interventions

Intervention 1: Intervention group1: Group treated with normal saline serum. Intervention 2: Intervention group2: Group treated with half saline serum.

Eligibility

Sex/Gender

All

Age

No minimum to 18 Years

Inclusion criteria

Inclusion criteria: Age under 18years Blood suger obove 250 Ph< 7.3 Hco3< 18 Ketonuria

Exclusion criteria

Exclusion criteria: Blood Sodium level above 150 Blood sodium level umder 130 Referral patients from other centers

Design outcomes

Primary

Measure	Time frame
Correction of acidosis. Timepoint: In 24 hours after addmition. Method of measurement: chek of vbg every 2 hours.;Blood electrolyte changes. Timepoint: Every two hours. Method of measurement: blood test.;Blood sugar changes. Timepoint: every hour. Method of measurement: Blood sugar test.	—

Secondary

Measure	Time frame
Brain edema symptom. Timepoint: Frequent examination every 2 hours. Method of measurement: Examining clinical symptoms including changes in level of consciousness, headache and anisocoria.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Shiva, Siamak

Tabriz University of Medical Sciences

Shivas@tbzmed.ac.ir+98 41 3159 5050

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026