Skip to content

Comparing the effects of carbetocin and oxytocin in preventing postpartum hemorrhage

Comparing the effects of carbetocin and oxytocin in preventing postpartum hemorrhage in patients undergoing elective cesarean section: a double-blind randomized controlled trial.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231023059817N3
Enrollment
500
Registered
2024-07-21
Start date
2024-07-22
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum hemorrhage. Postpartum hemorrhage

Interventions

Intervention 1: Before the surgery and in order to minimize the drop in blood pressure caused by the spinal anesthesia method, 500 cc of normal saline 0.9% or Ringer's serum is infused for all patient

Sponsors

Pars Behrouzan Jam
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Candidates for elective cesarean section Patients Underwent spinal anesthesia Patients who have signed the informed consent forum

Exclusion criteria

Exclusion criteria: Severe underlying disease (heart-liver-kidney-pulmonary) Mental disabilities Caesarean section due to placenta accreta and previa

Design outcomes

Primary

MeasureTime frame
Postpartum hemorrhage. Timepoint: After and during delivery. Method of measurement: The difference in the amount of hemoglobin before and after surgery and the amount of urinary output according to the volume of fluid received along with clinical judgment.

Secondary

MeasureTime frame
The need for a second uterotonic drug. Timepoint: After and during delivery. Method of measurement: Medical examination.;The need for uterine massage. Timepoint: After and during delivery. Method of measurement: Medical examination.;Headache. Timepoint: After and during delivery. Method of measurement: Questions about the mother and the medical record.;Vertigo. Timepoint: After and during delivery. Method of measurement: Questions about the mother and the medical record.;Nausea and vomiting. Timepoint: After and during delivery. Method of measurement: Questions about the mother and the medical record.;Fainting. Timepoint: After and during delivery. Method of measurement: Questions about the mother and the medical record.;Flushing and feeling hot. Timepoint: After and during delivery. Method of measurement: Questions about the mother and the medical record.;Chill. Timepoint: After and during delivery. Method of measurement: Questions about the mother and the medical record.;Itching. Timepoint: After and during delivery. Method of measurement: Questions about the mother and the medical record.;The taste of metal. Timepoint: After and during delivery. Method of measurement: Questions about the mother and the medical record.;Palpitation. Timepoint: After and during delivery. Method of measurement: Questions about the mother and the medical record.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohadese Dashtkoohi

Tehran University of Medical Sciences

mohade3dasht@gmail.com+98 21 2253 9892

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026