Dry eye. Dry eye syndrome
Conditions
Interventions
Intervention 1: Intervention group: Patients with dry eyes, will receive in the right eye, one drop (0.05 cc) of exosome derived from limbal mesenchymal stem cells with a concentration of 0.01 micro l
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with complaints of burning or itching or feeling of a foreign body in the eye Moderate and severe dry eye severity Age between 18-70 years
Exclusion criteria
Exclusion criteria: Previous history of eye surgery Any disease that suppresses the immune system Pregnancy and breastfeeding Eyelid abnormalities Use of eye drops in the past year except artificial tears and lubricating ointments Use of systemic drugs that affect the tear film in last three months Use of systemic steroid in the last three months Use of contact lenses in the last three months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dry eye. Timepoint: Before the intervention, 4 and 12 weeks after the intervention. Method of measurement: Based on the ocular surface disease index questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHossein Aghaei
Iran University of Medical Sciences
Outcome results
None listed