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Investigating the effect of curcumin tablets on pain, blood pressure and blood coagulation in patients undergoing surgery for benign prostatic hyperplasia through urethral incision

Investigating the effect of curcumin tablets on pain, blood pressure and blood coagulation in patients undergoing surgery for benign prostatic hyperplasia through urethral incision

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231022059810N1
Enrollment
184
Registered
2023-12-06
Start date
2023-11-22
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperplasia of prostate. Enlarged prostate

Interventions

Intervention 1: In the control group, 25 mg Pethidine ampoule every 8 hours and a placebo pill will be prescribed daily. Intervention 2: In the intervention group, in addition to 25 mg Pethidine ampou

Sponsors

Ghoum University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who have undergone prostate urethral resection surgery Not having coagulation disorders Not having an allergy to curcumin Not having drug addiction

Exclusion criteria

Exclusion criteria: Abnormal bleeding after surgery (more than 300 cc) Criticality of the patient's vital signs

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Immediately before the intervention and every 6 hours after the intervention until discharge. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Blood pressure. Timepoint: Immediately before the intervention and every 6 hours after the intervention until discharge. Method of measurement: Vital Sign Monitoring Device.;Blood coagulation tests. Timepoint: Immediately before the intervention and every 24 hours after the intervention until discharge. Method of measurement: Using PT, PTT, INR laboratory tests.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtye Babaii

Ghoum University of Medical Sciences

a.babaii1400@gmail.com+98 25 3107 1100

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026