Condition 1: Open Heart Surgery using cardiopulmonary pump. Condition 2: Coronary artery bypass grafting. Postprocedural cerebrovascular infarction during cardiac surgery Atherosclerosis of autologous vein coronary artery bypass graft(s) with unspecified angina pectoris
Conditions
Interventions
Intervention 1: Intervention group: High flow group: In this group of patients, a flow rate of 2.6 liters per square meter per minute is used. Intervention 2: Control group: Normal flow group: In this
Sponsors
Semnan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Admission in the Open Heart ICU of Kowsar hospital Candidate for undergoing open heart surgery Obtaining a written consent for entering to the study
Exclusion criteria
Exclusion criteria: Patients with EF under 30% Patients who need Intra-aortic balloon pump Any unpredictable event during the surgery or Malfunction of Cardiopulmonary pump Aorta clamping lasts more than 2 hours The whole surgery lasts more than 3 hours Patients with history of CVA Patients with Congestive Heart Failure Patients with the history of chronic kidney disease and undergoing dialysis Patients with the history of chronic renal failure or undergoing hemodialysis Due to the fact that during the surgery the amount of PFR changes depending on the conditions of the operation, in case of fluctuation, the PFR may reach a level that reaches another group
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood Urea Nitrogen. Timepoint: 1 day before and 1 day after surgery. Method of measurement: Blood sample test.;Serum Creatinine. Timepoint: 1 day before and 1 day after surgery. Method of measurement: Blood sample test.;Alkaline phosphatase serum level. Timepoint: 1 day before and 1 day after surgery. Method of measurement: Blood sample test.;Aspartate aminotransferase serum level. Timepoint: 1 day before and 1 day after surgery. Method of measurement: Blood sample test.;Alanine transaminase serum level. Timepoint: 1 day before and 1 day after surgery. Method of measurement: Blood sample test.;The consciousness level of patient. Timepoint: Before surgery in OR and after surgery in recovery room. Method of measurement: The consciousness level of patient, which is evaluated by anesthesiologist in 4 levels. 1.Patient is alert: the patient is awake with his eyes open and answers the questions. It doesn't matter if the answers are imprecise or incorrect. 2. Responds to the Verbal stimulus: the patient only uses unintelligible sounds in answering the questions. 3. Responds to the pain stimulus: the patient only responds to pain. This response is either associated with the removal of the pain agent or only with stretching and expansion in the limbs. 4. No response: The patient is without any response to sound and pain.;Cerebral Oxygenation. Timepoint: During surgery. Method of measurement: Cerebral Oximeter.;Serum electrolytes level (Sodium, potassium and calcium). Timepoint: Before , during(every 30 minutes) and after surgery. Method of measurement: Blood sample test.;Serum Lactate Level. Timepoint: Before , during(every 30 minutes) and after surgery. Method of measurement: Blood sample test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMuhamad Frouzeshfard
Semnan University of Medical Sciences
Outcome results
None listed