Coronary artery disease with angina pectoris. Atherosclerotic heart disease of native coronary artery with angina pectoris
Conditions
Interventions
Intervention 1: Intervention group: In the intervention group, patients will first receive 1 mg of colchicine (produced by Hashtgerd-Iran Mofid Pharmaceutical Company) 12 to 24 hours before the study
Sponsors
Khoram-Abad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Suffering from stable and unstable angina pectoris and myocardial infarction without ST segment elevation diagnosed by a cardiologist and a candidate for coronary angiography Not taking colchicine due to other diseases such as gout Not having a history of myelodysplasia Not taking corticosteroids or non-steroidal anti-inflammatory drugs except aspirin for 3 days before Absence of malignancy or active infection
Exclusion criteria
Exclusion criteria: Being allergic to colchicine Not being a candidate for angioplasty after angiography Glomerular filtration below 30 ml/min
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Troponin. Timepoint: Troponin measurement is done 12 to 24 hours before the angioplasty procedure and also 24 hours after the procedure. Method of measurement: The level of troponin will be measured 12 to 24 hours before the procedure, exactly before receiving the first dose of the drug or placebo, and also 24 hours after the procedure by the laboratory technician with the HUBI TNI troponin quantitative kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyede Zohre Taheri
Khoram-Abad University of Medical Sciences
Outcome results
None listed