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Effect of corticosteroid in improving the results of embryo transfer in patients with endometriosis

Investigating the effect of corticosteroids in improving the results of embryo transfer in infertile patients with endometriosis in Akbarabadi Hospital, Tehran.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231015059725N1
Enrollment
110
Registered
2023-11-02
Start date
2022-03-01
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis and infertility.

Interventions

Intervention 1: Intervention group: Infertile endometriosis patients and candidates for embryo transfer treated with Differlin 3.75 in three doses with an interval of one month and then 10 weeks later

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age between 20 and 40 years Having endometriosis based on laparoscopic evidence

Exclusion criteria

Exclusion criteria: presence of severe sperm disorders in the patient's wife based on WHO 2021 criteria congenital or acquired uterine anomalies in the patient Suffering from thrombophilic diseases such as hemophilia Suffering from autoimmune diseases such as lupus The use of hormonal treatments by the individual Taking immunosuppressant drugs by the individual

Design outcomes

Primary

MeasureTime frame
Chemical pregnancy. Timepoint: Pregnancy check with beta hCG test two weeks after embryo transfer. Method of measurement: Beta hCG test.;Abortion. Timepoint: Continued pregnancy up to 20 weeks. Method of measurement: Examining the view of a live fetus with ultrasound.;Live birth. Timepoint: Pregnancy with a gestational age of more than 28 weeks. Method of measurement: Examining the live fetus with ultrasound.;Clinical pregnancy. Timepoint: Sonography 6 weeks later beta hCG positive. Method of measurement: Visualization of fetal heart rate by ultrasound.;Ongoing pregnancy. Timepoint: Continued pregnancy up to 12 weeks. Method of measurement: Ultrasound visualization of a live fetus at 12 weeks.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzadeh Shiralizadeh

Iran University of Medical Sciences

azadehshiralizadeh96@gmail.com+98 61 3627 2597

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026