Addiction. Other psychoactive substance related disorders
Conditions
Interventions
Intervention 1: Taking the full dose of methadone needed along with 1 to 2 teaspoons of herbal medicine Rahayesh(Barij essence, Kashan, Iran) per day for 4 weeks. Intervention 2: Control group: Receiv
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1- Patients with addiction (diagnosis based on DSM-IV criteria) who are treated with methadone Age 65-18 years The patient has not yet reduced the dose The patient should not take a high dose of methadone. The patient should only receive methadone treatment The patient's methadone treatment time is more than 6 months, that is, it has reached a point where it is no longer necessary to increase the dose for the patient (the patient is on a stable dose of methadone) The patient should receive a dose of methadone below 50 cc daily
Exclusion criteria
Exclusion criteria: 1. Every 7 days, the urine test for morphine, methamphetamine, hashish is checked, and if the test is positive, the patient is excluded from the study. The presence of certain diseases including hypothyroidism or hyperthyroidism and... High blood pressure (systolic pressure above 160 and diastolic pressure above 100 mmHg) Taking psychiatric and nerve drugs while studying, such as benzodiazepines, antidepressants, etc. Having psychotic symptoms6. Pregnant women Pregnant women Warfarin users People who are allergic to reading and report side effects caused by taking medicine while studying Use of anti-oxidant and anti-inflammatory drugs and supplements in the last 3 months and during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Withdrawal syndrome. Timepoint: At the beginning of the study, the second and fourth week of the study. Method of measurement: Clinical opiate withdrawal symptoms (COWS).;Craving. Timepoint: At the beginning of the study, the second and fourth week of the study. Method of measurement: Desire for Drug Questionnaire (DDQ craving). | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep quality. Timepoint: The beginning of the study, the second and fourth week of the study. Method of measurement: Pittsburgh Sleep Quality Index (PSQI).;Anxiety. Timepoint: The beginning of the study, the second and fourth week of the study. Method of measurement: Beck Anxiety Inventory (BAI).;Depression. Timepoint: The beginning of the study, the second and fourth week of the study. Method of measurement: Beck Depression Inventory (BDI).;Sexual desire. Timepoint: The beginning of the study, the second and fourth week of the study. Method of measurement: (IIEF)International index of erectile function questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHossein Akbary
Kashan University of Medical Sciences
Outcome results
None listed