Dry Eye Syndrome. Tear film insufficiency, Meibomian gland dysfunction
Conditions
Interventions
Intervention 1: Intervention group: Eye drops containing 15 cc of aqueous violet extract (two grams per hundred milliliters) for four weeks, one drop four times a day. Intervention 2: Control group: E
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with complaints related to dry eye syndrome OSDI questionnaire score is more than 12 and DEQ5 is more than 6 Consent to treatment with herbal and traditional medicines No active eye infection No history of refractive surgery Absence of pterygium disease Not using drugs with dry eye complications
Exclusion criteria
Exclusion criteria: The patient's unwillingness to receive treatment Allergy to herbal medicines Pregnancy Breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dry Eye symptoms. Timepoint: Before the intervention, 2 weeks and 4 weeks after the intervention. Method of measurement: Completion of the OSDI and DEQ5 questionnaires.;Tear break time (TBUT). Timepoint: Before the intervention and 4 weeks after the intervention. Method of measurement: The time of appearance of the first changes after the first blink in seconds with the keratograph.;Tear meniscus height. Timepoint: Before the intervention and 4 weeks after the intervention. Method of measurement: The height of the lacrimal crescent using the Keratograph values.;Redness of the conjunctiva. Timepoint: Before the intervention and 4 weeks after the intervention. Method of measurement: Using the Keratograph values.;Meibomian gland grade. Timepoint: Before the intervention and 4 weeks after the intervention. Method of measurement: Morphological changes of meibomian glands using the Keratograph values. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHaleh Ghooshkhanei
Mashhad University of Medical Sciences
Outcome results
None listed