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Effect of aerobic exercise and supplement on ROS and neurogenesis in depressed postmenopausal women

Effect of aerobic exercise and Aphrodite supplement on the level of some oxidative stress factors and neurogenesis of transmitters related to mental and psychological disorders of postmenopausal women with depression

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231009059661N1
Enrollment
200
Registered
2023-12-30
Start date
2023-11-01
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression. Other depressive episodes

Interventions

Intervention 1: Intervention group 1: twelve weeks aerobic exercise, from 50 pre cent of HRm(in first week) to 70 pre cent of that in last five weeks. Intervention 2: Intervention group 2: 12 weeks of

Sponsors

Islamic Azad University Isfahan(Khorasgan) branch research Deputy
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
55 Years to 60 Years

Inclusion criteria

Inclusion criteria: 6 months old LMP and serum estradiol less than 35 picogram per deciliter BMI between 26-29 Moderate depression using a questionnaire based on Beck anxiety inventory (BAI)

Exclusion criteria

Exclusion criteria: Not having any special chronic or systemic disorder

Design outcomes

Primary

MeasureTime frame
Malondialdehyde(MDA). Timepoint: Before starting the intervention and twelve weeks after that. Method of measurement: serum concentration of CGRP by ELISA method.;Superoxide dismutase(SOD). Timepoint: Before starting the intervention and twelve weeks after that. Method of measurement: serum concentration of superoxide dismutase by ELISA method.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarzaneh Taghian

Islamic Azad University

F_taghian@yahoo.com0098 31 335002352

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026