Gastroesophageal Reflux. Diseases of oesophagus, stomach and duodenum
Conditions
Interventions
Intervention 1: Intervention group: In the medicine group, we put 3 grams of medicine (1.5 grams of brown sumac and 1.5 grams of anise) as a mixture, divided into 6 capsules of 500 mg and 2 tablets ar
Sponsors
Institute of Medical History, Islamic and Complementary Medicine Studies
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients who have gastroesophageal reflux symptoms at least once a week (Heartburn and Regurgitation) Patients who do not complication from gastroesophageal reflux disease. People who have been diagnosed with reflux disease and have not taken medicine in the last 2 weeks and want to start anti-reflux treatment again.
Exclusion criteria
Exclusion criteria: Patients with regular glucocorticoid intake Pregnancy Breastfeeding The presence of signs and symptoms of danger in the patient's history, such as weight loss of more than 10% during the last three months Patients with a history of Barrett's disease History of esophageal, stomach, or intestinal cancer Patients with coagulation disorders Patients with acute peptic ulcer or its complications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of heartburn based on (QOLRAD) (FSSG). Timepoint: Severity of Heartburn before the start of the intervention, 2 and 4 weeks after the start of the intervention;. Method of measurement: Severity of Heartburn based on (FSSG) frequency scale for the symptoms of GERD ? (QOLRAD) Quality Of Life in Reflux and Dyspepsia.;Frequency of Heartburn based on (QOLRAD) (FSSG). Timepoint: Frequency of Heartburn before the intervention, 2 and 4 weeks after the intervention;. Method of measurement: Frequency of Heartburn based on (FSSG) frequency scale for the symptoms of GERD ? (QOLRAD) Quality Of Life in Reflux and Dyspepsia.;Severity of Regurgitation based on (QOLRAD) (FSSG). Timepoint: Severity of Regurgitation before the start of the intervention, 2 and 4 weeks after the start of the intervention;. Method of measurement: Severity of Regurgitation based on (FSSG) frequency scale for the symptoms of GERD ? (QOLRAD) Quality Of Life in Reflux and Dyspepsia.;Frequency of Regurgitation based on (QOLRAD) (FSSG). Timepoint: Frequency of Regurgitation before the intervention, 2 and 4 weeks after the intervention;. Method of measurement: Frequency of Regurgitation based on (FSSG) frequency scale for the symptoms of GERD ? (QOLRAD) Quality Of Life in Reflux and Dyspepsia. | — |
Secondary
| Measure | Time frame |
|---|---|
| Stomach temperament in terms of coldness, warmth, dryness and humidity. Timepoint: Before the start of the intervention and 4 weeks after the start of the intervention. Method of measurement: Stomach temperament questionnaires.;Drug side effects. Timepoint: Week 2 and 4 after the intervention. Method of measurement: Medication side effects questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMalihe zaman Momeniha
Iran University of Medical Sciences
Outcome results
None listed