Investigating the effectiveness of Lycopene on the Hemodynamic status of Coronary artery bypass graft surgery candidates

Investigating the effectiveness of Lycopene on the Hemodynamic status of Coronary artery bypass graft surgery candidates in Shahid Chamran Hospital, Isfahan in 2024

Status

Active, not recruiting

Phases

Phase 3

Study type

Observational

Source

IRCT

Registry ID

IRCT20231006059634N2

Enrollment

Registered

2024-11-29

Start date

2024-03-20

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamics of coronary bypass patients. Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris

Interventions

Intervention 1: Intervention group: Coronary bypass patients will be treated with Lycopene by Vitabiotics with a dose of 30 mg 12 hours before the operation. Intervention 2: Control group: Coronary by

Eligibility

Sex/Gender

All

Age

40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Coronary artery bypass graft surgery candidate Age between 40 and 70 years Having knowledge and consent to participate in the study

Exclusion criteria

Exclusion criteria: Pregnancy and breastfeeding Patients under ANH Addiction to psychotropics

Design outcomes

Primary

Measure	Time frame
Systolic blood pressure. Timepoint: Before induction of anesthesia, during the operation and then every 4 hours after the operation up to 48 hours during hospitalization in the ICU. Method of measurement: Based on launch with Arterline.;Diastolic blood pressure. Timepoint: Before induction of anesthesia, during the operation and then every 4 hours after the operation up to 48 hours during hospitalization in the ICU. Method of measurement: Based on launch with Arterline.;Mean arterial pressure. Timepoint: Before induction of anesthesia, during the operation and then every 4 hours after the operation up to 48 hours during hospitalization in the ICU. Method of measurement: Based on launch with Arterline.	—

Measure

Time frame

Systolic blood pressure. Timepoint: Before induction of anesthesia, during the operation and then every 4 hours after the operation up to 48 hours during hospitalization in the ICU. Method of measurement: Based on launch with Arterline.;Diastolic blood pressure. Timepoint: Before induction of anesthesia, during the operation and then every 4 hours after the operation up to 48 hours during hospitalization in the ICU. Method of measurement: Based on launch with Arterline.;Mean arterial pressure. Timepoint: Before induction of anesthesia, during the operation and then every 4 hours after the operation up to 48 hours during hospitalization in the ICU. Method of measurement: Based on launch with Arterline.

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Secondary

Measure	Time frame
Inotrope consumption. Timepoint: During the operation and then up to 48 hours during hospitalization in the ICU. Method of measurement: Based on the amount of inotrope injected.;Arrhythmia. Timepoint: During the operation and then up to 48 hours during hospitalization in the ICU. Method of measurement: View of ECG.;CRP level. Timepoint: During the operation and then up to 48 hours during hospitalization in the ICU. Method of measurement: Based on a blood test.	—

Measure

Time frame

Inotrope consumption. Timepoint: During the operation and then up to 48 hours during hospitalization in the ICU. Method of measurement: Based on the amount of inotrope injected.;Arrhythmia. Timepoint: During the operation and then up to 48 hours during hospitalization in the ICU. Method of measurement: View of ECG.;CRP level. Timepoint: During the operation and then up to 48 hours during hospitalization in the ICU. Method of measurement: Based on a blood test.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Naseri Nasab

Esfahan University of Medical Sciences

hosseinna1994@gmail.com+98 31 5261 0180

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026