Functional Constipation. Constipation
Conditions
Interventions
Intervention 1: Intervention group: Reuteflor oral sachet, each Reuteflor sachet contains 800 million active lyophilized cells of Lactobacillus roteri (equivalent to 8*10^8 CFU), 1 to 2 sachets per da
Sponsors
Bandare-abbas University of Medical Sciences
Eligibility
Sex/Gender
All
Age
2 Years to 12 Years
Inclusion criteria
Inclusion criteria: Children aged 2 to 12 years Having functional constipation based on Rome criteria 4 Not using probiotics, prebiotics or antibiotics 4 weeks before the start of the research No history of gastrointestinal surgery Lack of sensitivity or tolerance to Lactobacillus roteri (Reuteflor) Interest in participating in the study and consent of family/guardian
Exclusion criteria
Exclusion criteria: Children with organic digestive disorders or any other underlying disease that can affect bowel function. Children with mental disability Current use of medications that affect bowel function such as laxatives or antidiarrheals History of using probiotics, prebiotics or antibiotics 4 weeks before the start of the research Inability or unwillingness to comply with the study protocol or follow-up History of participating in a different clinical trial in the last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional Constipation based on ROME IV Criteria. Timepoint: Initial Presentation and Subsequent Observations on Days 7, 14, 21, and 28, as well as Two Months Post-Administration of Probiotics. Method of measurement: ROME IV Criteria. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamira Zakeri Shahvari
Bandare-abbas University of Medical Sciences
Outcome results
None listed