Hemostatic Efficacy of AriClot Powder in Postoperative Bleeding Reduction after Impacted Lower Third Molar surgery

Hemostatic Efficacy of AriClot Powder (absorbable modified starch) in Postoperative Bleeding Reduction after Impacted Lower Third Molar surgery: A Randomized Clinical Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20231004059609N1

Enrollment

Registered

2024-01-24

Start date

2024-01-21

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Haemorrhage after Impacted Lower Third Molar Extraction. Haemorrhage and haematoma complicating a procedure, not elsewhere classified

Interventions

Intervention 1: Intervention group: patients will undergo impacted lower third molar extraction. after tooth removal, patients in the intervention group will receive application of Ariclot powder dire

Eligibility

Sex/Gender

All

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: patients aged 18-35 having at least one fully mesioangular impacted mandibular third molar requiring surgical extraction

Exclusion criteria

Exclusion criteria: bleeding disorders use of anticoagulant medication severe periodontal disease history of allergic reactions to starch medical conditions such as renal, hepatic, or diabetic disorders a requirement of over 2 carpules of 2% lidocaine for anesthesia

Design outcomes

Primary

Measure	Time frame
Bleeding amount before reaching homeostasis. Timepoint: when no further bleeding is observed. Method of measurement: it will be Measured using pre-weighed sterile surgical gauzes placed directly on the site. gauzes will be weighed before and after use to determine grams of blood absorbed.;Bleeding time. Timepoint: when no further bleeding is observed. Method of measurement: it will be measured using a stopwatch from the time the tooth is removed and powder/gauze and pressure are applied until the bleeding stops completely.	—

Measure

Time frame

Bleeding amount before reaching homeostasis. Timepoint: when no further bleeding is observed. Method of measurement: it will be Measured using pre-weighed sterile surgical gauzes placed directly on the site. gauzes will be weighed before and after use to determine grams of blood absorbed.;Bleeding time. Timepoint: when no further bleeding is observed. Method of measurement: it will be measured using a stopwatch from the time the tooth is removed and powder/gauze and pressure are applied until the bleeding stops completely.

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Secondary

Measure	Time frame
Surgeon satisfaction with the hemostatic ability of the powder. Timepoint: when no further bleeding is observed. Method of measurement: This will be evaluated using a predefined scoring system based on surgeon satisfaction with the hemostatic ability of the powder. The scoring system consists of 4 scores ranging from 1 to 4. A score of 1 indicates poor bleeding control, a score of 2 indicates fair bleeding control, a score of 3 indicates good bleeding control and a score of 4 indicates excellent control of bleeding.;Delayed bleeding. Timepoint: 1 day and 1 week after surgery. Method of measurement: Patients will be followed up 1day and 1 week after surgery and will be asked about existence of delayed bleeding.	—

Measure

Time frame

Surgeon satisfaction with the hemostatic ability of the powder. Timepoint: when no further bleeding is observed. Method of measurement: This will be evaluated using a predefined scoring system based on surgeon satisfaction with the hemostatic ability of the powder. The scoring system consists of 4 scores ranging from 1 to 4. A score of 1 indicates poor bleeding control, a score of 2 indicates fair bleeding control, a score of 3 indicates good bleeding control and a score of 4 indicates excellent control of bleeding.;Delayed bleeding. Timepoint: 1 day and 1 week after surgery. Method of measurement: Patients will be followed up 1day and 1 week after surgery and will be asked about existence of delayed bleeding.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactPegah Farrahi

Shiraz University of Medical Sciences

Pegah.farrahi@gmail.com+98 71 3631 0895

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026