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Investigating and comparing the effect of subcutaneous and intradermal mesotherapy on improving pain and function in patients with osteoarthritis of the knee: a randomized clinical trial study

Investigating and comparing the effect of subcutaneous and intradermal mesotherapy on improving pain and function in patients with osteoarthritis of the knee: a randomized clinical trial study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231003059603N1
Enrollment
50
Registered
2023-10-10
Start date
2023-10-22
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis. Osteoarthritis of knee

Interventions

Intervention 1: Intervention group: 2 sessions per week for 3 weeks, subcutaneous mesotherapy with 1 ml of piroxicam and 2 ml of lidocaine2% in 6 acupuncture points around the knee along with exercis

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with mild to moderate osteoarthritis of the knee based on the Kellgren Lawrence criteria aged between 40 and 70 years clinical symptoms for at least one month.

Exclusion criteria

Exclusion criteria: Patients who have a history of knee surgery. Patients who have undergone rehabilitation treatments in the last 3 months due to knee pain. Existence of neurological disease, infectious disease, cognitive disorder, malignancy, cardiac and nephrology disease pregnancy

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: before treatment, immediately after last session, one month after treatment. Method of measurement: Visual Analogue Scale questionnaire.;The degree of knee disability. Timepoint: before treatment, immediately after last session, one month after treatment. Method of measurement: Western Ontario and McMaster Universities Arthritis Index questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParisa Taheri

Esfahan University of Medical Sciences

Prs_taheri@yahoo.com+98 31 3668 0048

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026