Vitiligo.
Conditions
Interventions
Intervention 1: Intervention group: topical cream of Falcaria vulgaris extract, 3% w/w, once daily, for 3 months, apply topical to affected areas. Intervention 2: Control group: betamethasone (as Vale
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with mild to moderate vitiligo Patients who have at least two symmetric skin lesions Not suffering from skin diseases, such as allergies, etc. Not suffering from light-sensitive diseases such as lupus and porphyria, Not using photosensitizing drugs such as retinoids Patients who have not received systemic treatment for vitiligo in the past one month and during this period Patients with lesions that are homogeneous in terms of size, location, and duration of the lesion, and stable so that the lesion did not spread for at least the last 6 months.
Exclusion criteria
Exclusion criteria: Pregnancy and lactation Patients with severe vitiligo History of contact dermatitis Having other skin diseases that affect the study Patient dissatisfaction Case of drug allergy Face and axillary and inguinal region involvement Mentally retarded patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The size of lesions. Timepoint: At the beginning of the study (before the start of the intervention) and 1, 2 and 3 months after the use of topical treatments. Method of measurement: Based on the Vitiligo Area Scoring Index - using the hand unit and the amount of depigmentation of the lesion.;Repigmentation percent. Timepoint: 1, 2 and 3 months after the use of topical treatments. Method of measurement: Observationally by comparing with the photograph of the lesion before starting the intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| Noticeability of lesions. Timepoint: At the end of the study (3 months after the beginning of the intervention). Method of measurement: Vitiligo Noticeability Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSanam Javadzadeh
Tabriz University of Medical Sciences
Outcome results
None listed