Comparison of the effect of saline nebulizer 5% with Ventolin VS saline nebulizer 0.9% in the management of moderate asthma attack

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230930059568N1

Enrollment

Registered

2023-12-26

Start date

2023-11-22

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Moderate Asthma. Moderate persistent asthma, uncomplicated

Interventions

Intervention 1: Intervention group: In the intervention group, a vial of salbutamol (Ventolin, salbutamol sulfate 0.15 mg per kg with a minimum dose of 2.5 mg) in 2.5 mL of 5% hypertonic saline (minim

Eligibility

Sex/Gender

All

Age

1 Years to 18 Years

Inclusion criteria

Inclusion criteria: Age 1-18 years Moderate asthma attack Having a history of asthma symptoms (wheezing, shortness of breath and cough) that has been clinically confirmed

Exclusion criteria

Exclusion criteria: Heart disease Pneumonia Rheumatic disease

Design outcomes

Primary

Measure	Time frame
Improvement of Dyspnea. Timepoint: 0, 20, 40 and 60 minutes following treatment. Method of measurement: Observation.;Retraction. Timepoint: 0, 20, 40 and 60 minutes following treatment. Method of measurement: Observation.;SPO2. Timepoint: 0, 20, 40 and 60 minutes following treatment. Method of measurement: Pals oxymeter.;Heart rate. Timepoint: 0, 20, 40 and 60 minutes following treatment. Method of measurement: Measuring Heart rate.;Respiratory rate. Timepoint: 0, 20, 40 and 60 minutes following treatment. Method of measurement: Measuring respiratory rate.	—

Measure

Time frame

Improvement of Dyspnea. Timepoint: 0, 20, 40 and 60 minutes following treatment. Method of measurement: Observation.;Retraction. Timepoint: 0, 20, 40 and 60 minutes following treatment. Method of measurement: Observation.;SPO2. Timepoint: 0, 20, 40 and 60 minutes following treatment. Method of measurement: Pals oxymeter.;Heart rate. Timepoint: 0, 20, 40 and 60 minutes following treatment. Method of measurement: Measuring Heart rate.;Respiratory rate. Timepoint: 0, 20, 40 and 60 minutes following treatment. Method of measurement: Measuring respiratory rate.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Abbas Dabbaghzadeh

Mazandaran University of Medical Sciences

dabbaghzadeh@mazums.ac.ir+98 11 3334 2334

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026