Skip to content

The effect of vitamin D supplementation on the treatment of head and neck cancer patients

Evaluation of vitamin D supplementation on the treatment of patients with head and neck Squamous-Cell Carcinoma (SCC)

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230926059515N1
Enrollment
110
Registered
2023-10-07
Start date
2022-05-22
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and Neck Squamous-Cell Carcinoma. Malignant neoplasm of connective and soft tissue of head, face and neck

Interventions

The intervention group was supplemented with vitamin D (manufactured by Ariafarmed Peshgaman Salamat Pharmaceutical Company) at a dose of 2000 units per day and the control group (second) received pla

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients with histopathologically proven head and neck squamous cell carcinoma Age 20 to 75 years

Exclusion criteria

Exclusion criteria: Previous use of vitamin D supplements History of previous chemoradiotherapy Allergy to vitamin D supplements The presence of metastasis Failure to complete the standard treatment protocol

Design outcomes

Primary

MeasureTime frame
Tumor recurrence through clinical examination and imaging: Tumor recurrence in the primary site of the tumor underwent surgery, tumor recurrence in a place other than the primary tumor site, such as the involvement of other organs than the head and neck. Timepoint: 1.5 years. Method of measurement: Clinical examination or imaging if necessary.

Secondary

MeasureTime frame
Response to chemoradiotherapy by clinical examination and imaging: tumor volume reduced by less than 50% of the initial amount: no response, tumor volume reduced by more than 50% of the initial amount: partial response, no residual tumor: complete answer. Timepoint: 1.5 year. Method of measurement: Clinical examination or imaging if necessary.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiloofar Mohammadi

Kerman University of Medical Sciences

nmohammadi13@yahoo.com+98 34 3211 5780

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026