Evaluation of the effects of photobiomodulation therapy on oral ulcers induced by radiotherapy

Evaluation the Efficacy of Photobiomodulation Therapy with 660 nm Diode Laser on Treatment of Radiotherapy- Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized Clinical Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230923059490N1

Enrollment

Registered

2023-10-01

Start date

2023-11-22

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral mucositits induced by radiotherapy to head and neck. Oral mucositis (ulcerative) due to radiation

Interventions

Intervention 1: Intervention group: patients with oral mucositis receiving photobiomodulation therapy with low level 660 nm diode laser. Intervention 2: Control group: Patients with oral mucositis rec

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with equal or more than 60% Karnofsky Performance Status Life expectancy equal or more than 3 months Clinical confirmation of oral mucositis with minimum grade 1

Exclusion criteria

Exclusion criteria: Previous history of radiotherapy to head and neck region Other systemic diseases

Design outcomes

Primary

Measure	Time frame
Oral mucositis grade measured by WHO scale. Timepoint: Before intervention, during treatment session , 4 weeks after intervention. Method of measurement: WHO (World Health Organization) grading Scale for oral mucositis.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNeda Hakimiha

Shahid Beheshti University of Medical Sciences

ned.hakimiha@gmail.com+98 21 2274 9221

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026