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Transcranial direct current stimulation and sertraline on obsessive-compulsive disorder

Effect of transcranial direct current stimulation on sertraline composition on the severity of symptoms of obsessive-compulsive disorder

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230922059487N1
Enrollment
50
Registered
2023-11-17
Start date
2023-11-21
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obsessive-compulsive disorder. Obsessive-compulsive disorder

Interventions

Intervention 1: Control group: This group receives passive TDCS only. In this group, there are 25 people who receive passive TDCS only, in a room in a psychiatric clinic that is equipped with equipmen

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with obsessive-compulsive disorder with minimal literacy at the level of reading and writing Patients with obsessive-compulsive disorder aged over 18 and under 65 years Patients suffering from obsessive-compulsive disorder who, based on the Padua questionnaire, have obsessive thoughts of contamination, harming themselves and others, or self-control Patients suffering from obsessive-compulsive disorder whose severity is moderate or severe based on the Padua questionnaire Patients with obsessive-compulsive disorder who took sertraline (at least 100 mg) during the study.

Exclusion criteria

Exclusion criteria: Patients with a recent history of brain surgery, neurological conditions associated with brain abnormalities (such as traumatic brain injury, recent stroke and tumor), devices implanted in the skull, having hearing aids that are not removable, active skin lesions on the scalp History of migraine, epilepsy and convulsions, unstable medical or psychiatric conditions (such as psychotic disorders, bipolar disorder, suicidal thoughts or attempted suicide in the last 4 weeks) Patients with current use of benzodiazepines, anticonvulsants, lithium carbonate, psychostimulants, dextromethorphan, pseudoephedrine, or recreational drug use Patients treated with any type of neuromodulation treatment (such as ECT, transcranial magnetic stimulation or TDCS) during the last 3 months

Design outcomes

Primary

MeasureTime frame
Obsessive-practical score in the Padua questionnaire. Timepoint: At the beginning of the study (before the start of the intervention), after 8 sessions, 16 sessions and then one month after the 16th session. Method of measurement: The Padua questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Ali Hossein Tehrani

Arak University of Medical Sciences

m.hosseintehrani@arakmu.ac.ir+98 86 3861 4254

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026