Coronary artery disease. Atherosclerosis of coronary artery bypass graft(s), unspecified, with angina pectoris
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Both male and female patients within the age of 40 to 70 will be eligible. Patients will be included based upon clinical symptoms, coronary angiography, 12 lead ECG, echocardiogram and routine basic blood investigations which will be complete blood count. Patients will be included based upon renal function tests, liver function tests, clotting profile, hepatitis screening. Patients will be included based upon blood grouping and cross match, chest x-ray and left ventricle ejection fraction =35% determined by echocardiogram.
Exclusion criteria
Exclusion criteria: Emergent surgery due to unstable angina Hemodynamically unstable patients. Patients on preoperative inotropic support. Patients pericardial effusion and perioperative lung complication. Patient on steroids and bronchodilators. Patients with endocrine abnormalities such as hyper or hypothyroidism. Patients with neurological disability and/or musculoskeletal disorder. Concomitant valve disease. Patients having dysrhythmias or on permanent pacemaker and intra-aortic balloon pump. Anemic patient with hemoglobin less than 10 grams /dl. Pregnancy Obesity class II & III according to BMI >40kg/m2 Patients having Asthma, COPD and Interstitial Lung Disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified medical research council dyspnea scale. Timepoint: Baseline, preoperative after 2 weeks of treatment, postoperatively on day 1st, 2nd and before discharge from hospital. Method of measurement: Chest expansion by flexi-curve, modified medical research council dyspnea scale for dyspnea evaluation, pulmonary complication evaluation by using Chest Xray, Dyspnea (D-12) Questionnaire for shortness of breath. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Functional mobility 2. Chest expansion 3. Dyspnea 4. pulmonary complications 5. length of hospital stay. Timepoint: Baseline, preoperatively after 2 weeks of treatment, postoperatively on day 1st, 2nd and before hospital discharge. Method of measurement: Functional mobility scale, Chest expansion by flexi-curve, modified medical research council dyspnea scale for dyspnea evaluation, pulmonary complication evaluation by using Chest Xray, Dyspnea (D-12) Questionnaire for shortness of breath. | — |
Countries
Pakistan
Contacts
National Hospital and Medical Centre Lahore Punjab