Osteopenia of prematurity. Other specified disorders of bone density and structure, other site
Conditions
Interventions
Intervention 1: Intervention group: The intervention group will be prescribed prophylactic caffeine citrate (20 mg/kg intravenously as an initial dose on the first day of birth and then 5 mg/kg daily
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 56 Days
Inclusion criteria
Inclusion criteria: Infants with a fetal age of less than 32 weeks Infants who had spontaneous breathing
Exclusion criteria
Exclusion criteria: Neonates with major congenital anomalies Asphyxiation Hypoxic Ischemic Encephalopathy stage 2 , 3 Intrauterine growth retardation Neonates with cholestasis Neonates with neuromuscular disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum levels of calcium. Timepoint: Serum levels of calcium was evaluated at two weeks and also at the time of discharge. Method of measurement: The records of patients.;Serum levels of phosphors. Timepoint: Serum levels of phosphor was evaluated at two weeks and also at the time of discharge. Method of measurement: The records of patients.;Serum levels of alkaline phosphatase. Timepoint: Serum levels of alkaline phosphatase was evaluated at two weeks and also at the time of discharge. Method of measurement: The records of patients. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh sadat Nayari
Tehran University of Medical Sciences
Outcome results
None listed