Investigating the simultaneous effect of Phototherapy with oral Zinc Sulfate on the amount of Bilirubin change in infants with Hyperbilirubinemia and the duration of their treatment in Baharlou Hospital.

Investigating the effectiveness of Zinc Sulfate during the duration of the need for Phototherapy in infants with Congenital Jaundice

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230914059430N1

Enrollment

320

Registered

2024-01-29

Start date

2024-02-20

Completion date

Unknown

Last updated

2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital Jaundice. Neonatal jaundice from other and unspecified causes

Interventions

Intervention 1: Intervention group: Receiving oral zinc sulfate syrup 1 cc/kg, each cc containing 1 mg of zinc while performing phototherapy, which is checked for 48 hours. Intervention 2: Control gro

Eligibility

Sex/Gender

All

Age

1 Days to 14 Days

Inclusion criteria

Inclusion criteria: All full-term babies without risk factors born with Neonatal Jaundice

Exclusion criteria

Exclusion criteria: Lack of parental consent The presence of major risk factors in the baby, including Cardiovascular, Pulmonary, Renal defects, etc.

Design outcomes

Primary

Measure	Time frame
Total Bilirubin. Timepoint: Measurement of serum total bilirubin level at the beginning of the study (before the start of the intervention), 2 and 14 days after the start of oral zinc sulfate intake. Method of measurement: Blood examination.;Zinc Sulfate level in serum. Timepoint: Immediately before and after phototherapy depending on the duration of phototherapy. Method of measurement: Blood examination.	—

Measure

Time frame

Total Bilirubin. Timepoint: Measurement of serum total bilirubin level at the beginning of the study (before the start of the intervention), 2 and 14 days after the start of oral zinc sulfate intake. Method of measurement: Blood examination.;Zinc Sulfate level in serum. Timepoint: Immediately before and after phototherapy depending on the duration of phototherapy. Method of measurement: Blood examination.

—

Secondary

Measure	Time frame
The duration of receiving phototherapy. Timepoint: Up to 14 days after the study. Method of measurement: Medical record.;The length of hospitalization. Timepoint: Up to 14 days after the study. Method of measurement: Medical record.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAsghar Ghorbani

Tehran University of Medical Sciences

aghorbani@sina.tums.ac.ir+98 912 321 1189

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026