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Investigating the effect of Gliclazide-MR on glycaemic control in type 2 diabetic patients

Comparing the effect of basal insulin with modified-release gliclazide on glycemic control in type 2 diabetic patients with HbA1C above 10%

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230910059395N1
Enrollment
90
Registered
2023-11-18
Start date
2023-12-22
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes. Diabetes mellitus due to underlying condition

Interventions

Intervention 1: Intervention group: For patients, in addition to the drugs they receive for glycemic control, gliclazide-MR 30 mg (produced by Actoverco pharmaceutical company) twice a day will be pre

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to No maximum

Inclusion criteria

Inclusion criteria: Type 2 diabetes patients with HbA1C above 10% Age over 30 years

Exclusion criteria

Exclusion criteria: Patients with kidney and liver failure Heart failure Stroke Pregnancy Previous receipt of gliclazide and insulin Gastric problems Consumption of sulfonylureas Urine ketone positivity while having symptoms of polyuria Diabetic ketoacidosis

Design outcomes

Primary

MeasureTime frame
HbA1C. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: High Performance Liquid Chromatography(HPLC).;Fasting blood sugar (FBS). Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: High Performance Liquid Chromatography (HPLC).;Two-hour blood sugar (BS 2hpp). Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: High Performance Liquid Chromatography (HPLC).

Secondary

MeasureTime frame
Excessive drinking and excessive urination. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: Interview.;Weight. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: Weight scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ebrahim Mohammmadi

Oroumia University of Medical Sciences

mohammadi.e@umsu.ac.ir+98 44 3245 7286

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026