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Controlled decompression effects in the patients with severe TBI: A Randomized Control Trial

Controlled decompression effects in the patients with severe TBI: A Randomized Control Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230907059376N1
Enrollment
52
Registered
2023-09-13
Start date
2022-08-13
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic brain injury. Diffuse traumatic brain injury

Interventions

Intervention 1: Intervention group: Standard surgical techniques were used to achieve a rapid craniotomy.The dura was entirely opened by a normal large craniotomy (12 to 15 cm), allowing the ICP to be

Sponsors

Afridi Medical Complex, Peshawar
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients with TBI between the ages of 18 and 75 Patients who gave informed permission Glasgow Coma Scale (GCS) score between 3 and 8 at admission

Exclusion criteria

Exclusion criteria: Initial need for bilateral craniotomy Preoperative GCS score of 3 with no improvement after treatment in the emergency room Presentation without attenuated respiration and blood pressure Combination of anoxia and hypotension with brain swelling caused by anoxia or hypotension and minor intracranial bleeding after injury Coagulation disorder or a history of aspirin intake and multiorgan malfunction

Design outcomes

Primary

MeasureTime frame
Global disability and recovery after traumatic brain injury. Timepoint: Baseline and after 6 months. Method of measurement: Extended Glasgow Outcome Scale (GOSE).

Countries

Pakistan

Contacts

Public ContactAbdul Hameed Khan

Royal Preston Hospital, Preston UK

drhameedkhan@gmail.com+44 1772 716565

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026