Glioma cancer. Disorder of central nervous system, unspecified
Conditions
Interventions
Intervention group: use of multiple MRI diagnostic methods (differentiating glioma cell types) to predict response to treatment based on changes in treatment volumes - control group: No use of multipl
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients suffering from types of glioma
Exclusion criteria
Exclusion criteria: Tumor recurrence and history of RT-CRT treatment Central Nervous System (CNS) disorders such as epilepsy and stroke Patients with missing data Patients whose total resection of the Tumor was not possible and left the follow-up study due to Disease recurrence and the need for special treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy of predicting response to chemo-radiotherapy (to detect improvement, progression, pseudo-progression). Timepoint: One-six month after treatment. Method of measurement: Magnetic Response imaging - Response Assessment in Neuro-Oncology (RANO) Criteria. | — |
Secondary
| Measure | Time frame |
|---|---|
| Therapeutic volumes based on RANO criteria. Timepoint: One and six months after chemo-radiotherapy. Method of measurement: The values of quantitative MRI indicators and treatment volumes can be calculated automatically by the software. The RANO Criteria is a decision-making rule in relation to the volumes and response to treatment. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactIraj Abedi
Esfahan University of Medical Sciences
Outcome results
None listed