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Comparison of the efficacy and side effects of Desmopressin melting tablets and nasal spray in the treatment of primary enuresis in children aged 6 to 12 years

Comparison of the efficacy and side effects of Desmopressin melting tablets and nasal spray in the treatment of primary enuresis in children aged 6 to 12 years

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230902059325N1
Enrollment
220
Registered
2024-03-07
Start date
2024-03-20
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enuresis. nonorganic enuresis

Interventions

Intervention 1: Desmopressin Acetate tablets are used sublingually from FERRING Company under the brand name of MELT , for patients under 7 years of age, the dose is 60 micrograms, and for patients ov

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 12 Years

Inclusion criteria

Inclusion criteria: 6 to 12 years old Single-symptom nocturnal enuresis Able to use nasal spray or sublingual tablets Completion of the informed consent form by the guardian or legal guardian At least two weeks before the start of the study, he did not receive any medicine

Exclusion criteria

Exclusion criteria: Having a history of organic urological disease, daily urinary incontinence, diabetes insipidus, or persistent urinary tract infection Having clinically significant renal, hepatic, gastrointestinal, pulmonary, cardiovascular, endocrine, or neurological disease that interferes with evaluation Using antibiotics, diuretics or any medicine that affects the concentration of urine Failure to complete the informed consent form

Design outcomes

Primary

MeasureTime frame
Nocturia frequency. Timepoint: The period before the study, during one month after starting the drug and the follow-up period three months later. Method of measurement: Recording wet or dry nights in a notebook, by parents.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Saadat

Mashhad University of Medical Sciences

Saadats@mums.ac.ir+98 51 3724 9423

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026