Skip to content

Effect of compund antioxidant medication (Sperigen tablet) on sperm DNA Fragmentation Index in infertile men aged 20 to 40 years

Effect of compund antioxidant medication (Sperigen tablet) on sperm DNA Fragmentation Index in infertile men aged 20 to 40 years of age

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230831059309N1
Enrollment
60
Registered
2023-10-23
Start date
2023-11-01
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

male infertility.

Interventions

Intervention group:patients treated with Sperigen drug (manufactured by Arvand Pharmed Company) one oral capsule every 12 hours for three months.This medicine contains of a variety of antioxidants suc

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Infertile men with abnormal spermogram (Idiopathic) age range 20 to 40 years absence of hormonal, anatomical and congenital anomalies of the urogenital system, lack of antioxidant medication usage or drugs affecting spermogram parameters such as nitrofurantoin, corticosteroids and antineoplastic.

Exclusion criteria

Exclusion criteria: Men with normal spermogram use of drugs, cigarrette and waterpipe smoking patients outside the specified age range varicocele patients with Diabete, thyroid problem or any other internal disease affectting spermogram

Design outcomes

Primary

MeasureTime frame
Percentage of sperm DFI , total sperm count and total motile sperm in semen analysis. Timepoint: Measurement of DNA fragmentation Index before starting and 3 months after taking the drug. Method of measurement: Sperm Chromatin Structure Assay lab test (SCSA).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNarges Ghaznavi Jahromi

Zahedan University of Medical Sciences

n.ghaznavi@zaums.ac.ir+98 71 3233 1897

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026