Patient undergoing Elective abdominal cholecystectomy.
Conditions
Interventions
Intervention group:.
Sponsors
Self Sponsored
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: • Healthy Pakistani individuals between ages 18-60 years undergoing elective abdominal cholecystectomy. • Patients in classes I and II of the American Society of Anesthesiologists (ASA) scale.
Exclusion criteria
Exclusion criteria: • Not of Pakistani origin • Extremes of age • Patients in classes III, IV, V &, and VI of the ASA scale.• Patient with deranged Liver & renal function test (LFT/RFT) • Pre-operative morphine consumption• Patients on medication with immunosuppressive drugs, Non-steroidal anti-inflammatory drugs, or steroids if taking should stop them one week before surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To prove that lidocaine is a safe anesthetic adjuvant helps in early recovery and decreases the hospital load.by early mobilization. Timepoint: Samples will be taken at 0, 2, 4 & 6 hrs after the surgery. Method of measurement: BP by sphygmomonometer & plasma level of drugs by HPLC, Interleukin levels by ELISA kit, Genotyping by PCR & RFLP.;Analgesia. Timepoint: VAS. Method of measurement: Facial expression, then after 8 hours through verbel questions. | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory markers. Timepoint: IL levels decline earlier. Method of measurement: ELISA Kit. | — |
Countries
Pakistan
Contacts
Public ContactAyesha Afzal
Wah Medical College
Outcome results
None listed