Polyneuropathy. Drug-induced polyneuropathy
Conditions
Interventions
Intervention 1: Intervention group: 28 patients with polyneuropathy caused by vincristine who will be treated with 20 mg Duloxetine in the first week and after one week the dose will be increased to 4
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
5 Years to 18 Years
Inclusion criteria
Inclusion criteria: Patients with an age range between 5 and 18 years patients with Cancer who have been treated with vincristine Patients who have complications and clinical symptoms of CIPN according to the clinical diagnosis of the relevant oncologist.
Exclusion criteria
Exclusion criteria: present other underlying polyneuropathies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electrodiagnosis test findings in the investigation of polyneuropathy. Timepoint: At the time of visit (before the start of the intervention), 2 months after receiving the intervention. Method of measurement: EMG AND NCS device.;Findings from the questionnaire : Pediatric modified total neuropathy score. Timepoint: At the time of visit (before the start of the intervention), 2 months after receiving the intervention. Method of measurement: Pediatric modified total neuropathy score questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug side effects. Timepoint: At the beginning of the study, before the start of the intervention and 14 days and 30 days after the intervention, in person and in all stages, in the form of free telecommunication between the patient and the relevant doctor. Method of measurement: Questioning the patient and clinical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAtefeh raeisi mohammadi
Shahid Beheshti University of Medical Sciences
Outcome results
None listed