Appropriate dose of sodium thiopental for induction of anesthesia.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ASA Class I and II ASA Class III if it is due to BMI more than 40 BMI more than 25 obtaining informed consent
Exclusion criteria
Exclusion criteria: Patients with age less than 20 years or more than 60 years Discontentment with the project ASA Class IV and V Patients with unstable hemodynamics, hemorrhagic shock and heart failure Recent abuse of morphine or any other drugs Patients with porphyria, asthma, uncontrolled hypertension and hypothyroidism Patients with lowering of consciousness Patients with drug allergies Patients requiring second laryngoscopy or failed intubation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bispectral Index. Timepoint: Before induction of anesthesia, after injection of sodium thiopental, three minutes after induction of anesthesia. Method of measurement: BIS monitoring. | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart Rate. Timepoint: Before induction of anesthesia, after injection of sodium thiopental, three minutes after induction of anesthesia. Method of measurement: Pulse oximetry.;Mean Arterial pressure. Timepoint: Before induction of anesthesia, after injection of sodium thiopental, three minutes after induction of anesthesia. Method of measurement: NIBP monitoring. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tehran University of Medical Sciences