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Investigating the appropriate dose of sodium thiopental for induction of anesthesia

Investigating the appropriate dose of sodium thiopental for induction of anesthesia in patients with BMI greater than 25 who undergo surgery with tracheal intubation

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230825059254N1
Enrollment
90
Registered
2023-09-30
Start date
2023-10-23
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Appropriate dose of sodium thiopental for induction of anesthesia.

Interventions

Intervention 1: Intervention group: In the first intervention group, sodium thiopental was calculated and injected based on total body weight to induce anesthesia. Intervention 2: Intervention group:

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: ASA Class I and II ASA Class III if it is due to BMI more than 40 BMI more than 25 obtaining informed consent

Exclusion criteria

Exclusion criteria: Patients with age less than 20 years or more than 60 years Discontentment with the project ASA Class IV and V Patients with unstable hemodynamics, hemorrhagic shock and heart failure Recent abuse of morphine or any other drugs Patients with porphyria, asthma, uncontrolled hypertension and hypothyroidism Patients with lowering of consciousness Patients with drug allergies Patients requiring second laryngoscopy or failed intubation

Design outcomes

Primary

MeasureTime frame
Bispectral Index. Timepoint: Before induction of anesthesia, after injection of sodium thiopental, three minutes after induction of anesthesia. Method of measurement: BIS monitoring.

Secondary

MeasureTime frame
Heart Rate. Timepoint: Before induction of anesthesia, after injection of sodium thiopental, three minutes after induction of anesthesia. Method of measurement: Pulse oximetry.;Mean Arterial pressure. Timepoint: Before induction of anesthesia, after injection of sodium thiopental, three minutes after induction of anesthesia. Method of measurement: NIBP monitoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmirhossein Farhadi

Tehran University of Medical Sciences

am.farhady@gmail.com0098 21 61190

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026