Intraoperative sedation and analgesia. Thr drug under study will be given as adjuvant to anesthesia to produce sedation and analgesia and reduce the dose of anesthetic agents, analgesic and drugs for neasea & vomiting.
Conditions
Interventions
Intervention group: intervention Group will be administered 1µg/kg dexmedetomidine hydrochloride intravenously over 10 min as a bolus just before the induction in addition to the standard anaesthes
Sponsors
Islamic International Medical College and Wah medical college
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ASA I &II Pakistani origin
Exclusion criteria
Exclusion criteria: No co-morbidity Non pregnant females
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative sedation and analgesia. Timepoint: beore interventiona and at 1/2 an hour interval and at 2hrs interval. Method of measurement: Ramsay Sedation scale, Visual analogue scale and polymorphism in genes.;Genotyping and Polymorphism in Receptor gene and in enzyme gene. Timepoint: Polymorphism cam be studies both in control and study group in blood sample of 2hsr interval. Method of measurement: Drug concentration will be meausred at 30 min and at 2hrs interval in both groups. | — |
Countries
Pakistan
Contacts
Public ContactBrig (R) Dr Akbar Waheed
Islamic International Medical College and Wah medical college
Outcome results
None listed