Bronchopulmonary dysplasia. Bronchopulmonary dysplasia originating in the perinatal period
Conditions
Interventions
Intervention 1: Intervention group: treatment with inhaler Budesonide through jet nebulizer (250 mcg every 12 hours) for 7 days. Intervention 2: Control group:prescribe 3 cc of 0.9% normal saline ne
Sponsors
Karaj University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 1 Days
Inclusion criteria
Inclusion criteria: Premature neonates between 24 and 32 weeks
Exclusion criteria
Exclusion criteria: Weight Less than 500 grams or more than 1500 grams Neonate with fatal congenital abnormalities or disorders and congenital heart and lung diseases Pneumothorax prior to randomization clinical evidence of early onset sepsis prior to randomization
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bronchopulmonary dysplasia. Timepoint: 36 weeks PMA or discharge to home, whichever occurred first. Method of measurement: According to the NICHD2001 ,The need for supplemental oxygen at 28 PMA.;Mortality. Timepoint: daily. Method of measurement: until discharge. | — |
Secondary
| Measure | Time frame |
|---|---|
| The duration of hospitalization. Timepoint: Discharge Time. Method of measurement: The number of days of hospitalization records.;Duration of need for oxygen. Timepoint: Daily. Method of measurement: Days count before O2 discontinue.;Duration of non-invasive ventilation. Timepoint: Day. Method of measurement: days of non-invasive ventilation.;Duration of mechanical ventilation. Timepoint: daily. Method of measurement: days of mechanical ventilation.;Intraventricular hemorrhage. Timepoint: daily. Method of measurement: based on cranial ultrasonography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactKobra Hosseini
Karaj University of Medical Sciences
Outcome results
None listed