Incidence of Delirium After Coronary Artery Bypass Surgery. Postoperative delirium
Conditions
Interventions
Intervention 1: Intervention group (Drug Group): 1 Oral tablet of Melatonin 10 mg manufactured by Jalinous Iran company will be taken at night from 3 days before surgery and up to 5 days after surgery
Sponsors
Karaj University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients over 18 years of age, whose blood supply disorder to the heart makes them candidates for Coronary Artery Bypass Graft surgery Patients who have no problem understanding Persian language Signing the consent form by the patient (Consent is obtained from patients in written and verbal form)
Exclusion criteria
Exclusion criteria: People who have a history of allergic reaction to Melatonin or other ingredients in the pill Patients who suffered cardiac and respiratory arrest Patients who Have a history of mental disorders such as Psychosis and Mental Retardation Patients who take Antipsychotic drugs Patients with a history of Seizures Patients with a history of Delirium Patients with Alzheimer's Patients with severe Kidney and Liver failure Patients with Alcohol or drug addiction Patients who need reoperation due to abnormal bleeding Patients who are deaf Patients who do not have the ability to speak to answer the questions in the questionnaire Patients who are unable to swallow oral Melatonin Patients who are candidates for emergency surgery Pregnant and Lactating women If older people had medicines that interfered with my research Older people who are not able to participate in this plan for any reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of Delirium after surgery during the first 5 days after surgery. Timepoint: Investigation and recognition of confusion and monitoring of Delirium in patients of special care department is done on the day of operation and up to two days after the operation. Method of measurement: The confusion assessment-special care (CAM-ICU) questionnaire is used to investigate and recognize confusion and monitor delusions. | — |
Secondary
| Measure | Time frame |
|---|---|
| Measuring the intensity of delirium. Timepoint: After the diagnosis of delirium until two days after the operation, its severity is checked further. Method of measurement: Confusion Assessment Method-severity (CAM-S) questionnaire.;Measuring the level of alertness and the patient's responses to stimuli (Eye response - verbal response - motor response). Timepoint: Daily from 3 days before surgery to 5 days after. Method of measurement: Glasgow Coma Scale (GCS) Scoring system.;Check the quality of sleep. Timepoint: Daily from 3 days before surgery to 5 days after. Method of measurement: Epworth Sleep scale questionnaire (ESS).;Examining the pain intensity of patients. Timepoint: Daily from 3 days before surgery to 5 days after. Method of measurement: Numeric Rating Scale questionnaire (NRS).;Duration of hospitalization in the intensive care unit. Timepoint: daily from the day after surgery. Method of measurement: Counting the number of days a person is hospitalized in the intensive care unit of the hospital after surgery and based on the patient's admission file.;Duration of hospitalization. Timepoint: daily from the day after surgery. Method of measurement: Counting the number of days a person is hospitalized in the intensive care unit of the hospital after surgery and based on the patient's admission file.;Measuring the duration of delirium. Timepoint: From the time people are diagnosed with delirium until the time they recover. Method of measurement: Count the number of days. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Daei
Karaj University of Medical Sciences
Outcome results
None listed