Skip to content

Bio filler Vs Platelet rich plasma mesotherapy in the treatment of Peri-orbital hyperpigmentation

Biofiller Vs Platelet rich plasma mesotherapy in the treatment of Peri-orbital hyperpigmentation in patients presenting to outpatient department of dermatology in a tertiary care hospital-An RCT

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230816059168N1
Enrollment
42
Registered
2023-08-28
Start date
2023-09-01
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peri orbital hyperpigmentation. Other melanin hyperpigmentation

Interventions

Intervention 1: Intervention group 1: Topical eutectic mixture of local anesthetic cream will be applied over the patient’s face around eyes for 45?min. Ten milliliters of patient’s blood will be draw

Sponsors

Self
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: All patients with peri-orbital hyperpigmentation willing to participate in our study. Patients with peri-orbital hyperpigmentation, aged 18-65 years. Patients of Fitzpatrick skin type 1-4.

Exclusion criteria

Exclusion criteria: Patients having Hep B or C or HIV (as PRP and bio fillers are blood products and dealing with infected people can be hazardous for treating staff). Patients on immunosuppressant medications due to other diseases Pregnant women. Patients on anti-platelet or anticoagulants or fibrinolytics Patients using or have used other treatments for dark circles Patients of Fitzpatrick skin type 5 or 6

Design outcomes

Primary

MeasureTime frame
Photographs will be taken at the start of treatment and then 01 months after the last treatment. A validated photo-numeric scale for infraorbital dark circles proposed by M.M. O’Mahony et al, will be used in our study as objective measurement of periorbital dark circles intensity before and after treatment. Timepoint: 01 month after the last treatment. Method of measurement: Photo-numeric scale.

Countries

Pakistan

Contacts

Public ContactDr.Sakina Sadiq Malik

AM college Rwp

dazzlingdocsak2078@hotmail.com+92 321 5108737

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026