Skip to content

The effect of pre-operative oral pregabalin on pain after laparoscopic surgeries for endometriosis in women

Comparing the effect of oral pregabalin administration before surgery with placebo on pain after laparoscopic surgeriesEndometriosis of women in Rasoul Akram Hospital (S): a clinical trial study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230812059132N1
Enrollment
100
Registered
2023-11-05
Start date
2023-11-22
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic surgeries for endometriosis in women. Endometriosis

Interventions

Intervention 1: Intervention group: In the intervention group, oral pregabalin, a single dose of 150 mg, will be given to the patients one hour before the start of general anesthesia. questionnaire (V

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Patients aged between 18-45 years All patients who are candidates for laparoscopic endometriosis surgery Absence of drug addiction in the patient Lack of chronic and long-term use of opioid drugs or painkillers such as tramadol, diclofenac, naproxen Do not have psychiatric problems Insensitivity to pregabalin Performing surgery between 1401 and 1402 in Rasul Akram Hospital

Exclusion criteria

Exclusion criteria: have a contraindication for laparoscopy Have liver or kidney problems BMI above 30 Not able to express VAS score

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: All patients in two groups are evaluated after surgical recovery and immediately after recovery and at 2, 6, 12, 24 and 48 hours after surgery. Method of measurement: In terms of the amount of pain, they will be assessed by the visual pain assessment questionnaire (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElnaz Aghabeiki

Iran University of Medical Sciences

aghabeigi.e@iums.ac.ir+98 912 466 1996

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026