Chronic infected wounds – Infected diabetic foot ulcers – Infected pressure ulcers (decubitus ulcers) – Infected venous leg ulcers – Infected postoperative wounds – Local infection of skin and subcutaneous tissue due to chronic wounds. Type 2 diabetes mellitus with foot ulcer
Conditions
Interventions
Intervention 1: Intervention group: Intervention name: Topical gel of 8% standardized hydroalcoholic extract of the aerial part of Scrophularia striata (Teshivir)Standardization: Minimum 0.8% verbasco
Sponsors
Ilam University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age 18–65 years Chronic infected wound (diabetic foot ulcer, pressure ulcer, venous leg ulcer, or postoperative infected wound) lasting =4 weeks Wound area 2–20 cm² Ability to provide informed consent Hospitalized or regular outpatient follow-up
Exclusion criteria
Exclusion criteria: Active sepsis or septic shock Extensive necrosis or osteomyelitis Known allergy to Scrophulariaceae family Systemic corticosteroids or immunosuppressants Pregnancy or lactation Severe liver/kidney disease (Child C ?? eGFR<30) Malignant wound Non-compliant patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of wound surface area reduction from baseline to day 14. Timepoint: Day 0 (baseline), Day 7 and Day 14. Method of measurement: Standard photography with a ruler next to the wound (fixed distance of 30 cm, uniform lighting) ? Analysis with ImageJ software by two independent assessors blinded to the patient group; the average of the two final assessments is recorded. Daily camera calibration. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammadHossein Sahami Gilan
Ilam University of Medical Sciences
Outcome results
None listed