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Efficacy and safety of eptifibatide in patients with acute coronary syndrome

Efficacy and safety of bolus dose compared to standard dose of eptifibatide in patients with acute coronary syndrome: a randomized clinical trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230805059045N1
Enrollment
156
Registered
2023-08-19
Start date
2023-08-11
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute coronary syndrome. Other acute ischemic heart diseases

Interventions

Intervention 1: Control group: Receiving the standard dose of eptifibatide (bolus with infusion), that is, in addition to the bolus dose, a 12-18-hour infusion will be administered. Two separate doses

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients over 18 years old that have below characteristics patient with acute coronary syndrome patient treated with eptifibatide during angioplasty based on the diagnosis of the attending physician

Exclusion criteria

Exclusion criteria: If a patient with thrombocytopenia (platelets below 100,000) bleeding (gastrointestinal, cerebral, pulmonary) a history of intracranial events (neoplasm, arteriovenous malformation, cerebral aneurysm) severe renal dysfunction (creatinine clearance below 50) patients for whom Fibrinolytics have been prescribed in the last 24 hours

Design outcomes

Primary

MeasureTime frame
Efficacy and safety of reduced dose compared to standard eptifibatide in patients with acute coronary syndrome. Timepoint: Check the results after 90 days. Method of measurement: Efficacy and safety of the reduced dose compared to the standard eptifibatide in patients with acute coronary syndrome is how to check the mechanical outcomes after 90 days through echocardiography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaede Dadras

Rasht University of Medical Sciences

maede.dadras@gmail.com+98 13 3366 9064

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026