Skip to content

The Effect of Various dosage of Ketamin on postoperative pain in opiate-dependent patients undergoing orthopedic surgery

The Effect of various dosages of Ketamin on postoperative pain in opiate-dependent patients undergoing radius distal, femur, and tibia fracture orthopedic surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230804059031N1
Enrollment
50
Registered
2023-11-26
Start date
2023-11-05
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper and lower limb fractures.

Interventions

Intervention 1: Intervention group 1: 1mg/kg/ ketamine/C13H16ClNO/intravenous and at the beginning of surgical incision/1 shift/made by Rotex Germany company/. Intervention 2: Intervention group 2: 0.

Sponsors

Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 6 Years

Inclusion criteria

Inclusion criteria: Patients with a history of drug abuse 18-65 years

Exclusion criteria

Exclusion criteria: Patients with multiple trauma Consumption of alcohol and artificial drugs not derived from opium Patients should have continuous use of drugs other than narcotics Lack of patient consent for the study Non-cooperation of the patient after entering the study History of seizures or drug sensitivity to ketamine and other contraindications to ketamine History of cardiovascular diseases

Design outcomes

Primary

MeasureTime frame
Investigating the effectiveness of different doses of ketamine on postoperative pain in drug addicts undergoing orthopedic surgery for fractures of the distal radius, femur and tibia. Timepoint: 2, 6, 12 and 25 hours after the operation. Method of measurement: 1 to 10.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Khandan

Kashan University of Medical Sciences

khandan.dr@gmail.com+98 913 163 2580

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026