Itching caused by hypertrophic scars after burns. Pruritus
Conditions
Interventions
Intervention 1: Intervention group: subcutaneous injection of 1 ml of chlorpheniramine (mesotherapy) 10 mg along with 1 ml of lidocaine 2% in the healthy skin around the hypertrophic scar. Mesotherapy
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Being 18-65 years old Completing and signing the inform consent form Clinical diagnosis of hypertrophic burn scar At least two months have passed since the burn Burn less than 10% of TBSA Having pruritus Having history of second or third degree burns
Exclusion criteria
Exclusion criteria: Receiving a skin graft after a burn, patients suffering from wound infection due to burns, patients suffering from burns caused by chemicals or electric shock, suffering from perineal or facial burns, suffering from uncontrolled diabetes, inability to communicate and complete the questionnaire. having peripheral neuropathy or psoriatic skin diseases, history of epilepsy and taking anticonvulsant drugs, history of allergies and allergic reactions to used drugs, history of significant liver, kidney, brain, and cardiopulmonary disorders , pregnant women and lactating women, people who have cancer, people who are using anticoagulants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pruritus. Timepoint: before the intervention and one, three, seven, fourteen, twenty-eight days later and two months after the intervention. Method of measurement: Visual analog scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life of patients. Timepoint: Before the intervention, fourteen and twenty-eight days later and two months after the intervention. Method of measurement: DLQI quality of life questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZahra Setoodeh nia
Shiraz University of Medical Sciences
Outcome results
None listed