Melasma. Chloasma
Conditions
Interventions
Intervention 1: "Intervention group": includes people who receive Irsa cream. For 12 weeks, a thin layer of cream is applied on the spots in the morning and at night, and sunscreen is used during the
Sponsors
Shahed University
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Women aged 18-60 years Having clear lesions of melasma with expert approval
Exclusion criteria
Exclusion criteria: Pregnancy or breastfeeding Local or systemic treatment of melasma in the last 4 weeks Use of hormonal drugs (OCP and corticosteroids).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Color index of melasma lesions. Timepoint: Measurement of the color index of melasma lesions at the beginning of the study (before the start of the intervention) and 4?8?12?16 weeks after the start of the use of Irsa topical product. Method of measurement: Comparing the amount of skin darkening compared to healthy skin (natural skin color 0, brief darkness 1, mild darkness 2, moderate darkness 3, severe darkness 4) by observation, photography and megometer device. | — |
Secondary
| Measure | Time frame |
|---|---|
| The extent of melasma lesions. Timepoint: Measuring the extent of melasma lesions at the beginning of the study (before the start of theintervention) and 4?8?12?16 weaks after the start of using the Irsa topica lproduct. Method of measurement: Calculating the area of the lesion using MASI score and VISIOFACE. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactmasoomeh akhoondi ghahroodi
Shahed University
Outcome results
None listed