Patients with mechanical ventilation.
Conditions
Interventions
Intervention 1: Intervention Group under Mode A: Patients in the study area with pressure support were monitored while ensuring that the automatic tube compensation mode was turned off. The monitoring
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients treated with mechanical ventilation with SPONT mode. Peep should be 5 cm or less. Regulated Fio2 should be 40 percent or less. The patient should be eligible for general weaning. The range of the patient's support pressure should be at most 10 Cm H2o. The patient must be an adult. (age range 18 to 65 y/o) The patient has not received neuromuscular relaxants for the past 24 hours. At least two hours have passed since the last dose of bronchodilator received. The patient should be intubated with a suitable size ETT (suitable for age and sex). At least 48 hours have passed since the patient was put under mechanical ventilation. The trigger value of the ventilator should be 1-3 liters per minute.
Exclusion criteria
Exclusion criteria: A patient under ventilation with a type of ventilator that does not have the ability to adjust automatic tube compensation and support pressure. Patients with chronic obstructive pulmonary disease and acute respiratory distress syndrome. Lack of consent of the patient or the patient's guardian The patient has unstable hemodynamics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| P0.1: This pressure value is measured during the initial one-tenth of a second of inspiration and serves as an indicator of the diaphragm muscle's capability for weaning. The acceptable range for this value is 3 to 6 cmH2O. Timepoint: 15 and 30 minutes following the commencement of Phase A, as well as 15 and 30 minutes subsequent to the initiation of Phase B. Method of measurement: P0.1 is measured and displayed by the Hamilton ventilator device, and the researcher records it at the 15 and 30-minute marks for both the Mode A and Mode B conditions.;The Integrative Weaning Index (IWI) is a recently developed indicator used to forecast the weaning duration. This index evaluates the breathing pattern, breathing movements, oxygenation, and static lung capacity. It is computed using the formula IWI = (Static Compliance) × (SaO2) / RSBI. The calculated IWI value is then compared against a threshold of 25, with values exceeding this mark deemed acceptable. Timepoint: 15 and 30 minutes following the commencement of Phase A, as well as 15 and 30 minutes subsequent to the initiation of Phase B. Method of measurement: Static compliance and the Rapid and Shallow Breathing Index (RSBI) are gauged and exhibited by the Hamilton ventilator. Arterial blood oxygen saturation percentage (SaO2) is measured and displayed through monitoring and pulse oximetry. These parameters are then documented by the researcher at the 15 and 30-minute marks for both conditions A and B. Lastly, the Integrative Weaning Index is calculated and recorded using the formula IWI = (Static Compliance) × (SaO2) / RSBI.;Rapid and Shallow Breathing Index (RSBI): This index is utilized in the Weaning process and is derived by dividing the number of breaths by the tidal volume. The threshold for RSBI is set at 105, where values below this mark correlate with a higher likelihood of successful Weaning, while values exceeding it are linked to a greater probability of Weaning failure. Timepoint: 15 and 30 minutes follow | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactsomayeh Ghafari
Esfahan University of Medical Sciences
Outcome results
None listed