Investigating the effect of arginine mouthwash on salivary pH

Investigating the amount of salivary pH changes following the use of arginine mouthwash: a randomized clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230728058947N1

Enrollment

Registered

2023-08-09

Start date

2023-08-01

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

saliva pH.

Interventions

Intervention 1: Intervention group: 1% arginine mouthwash. Intervention 2: Intervention group: 0.5% arginine mouthwash.

Eligibility

Sex/Gender

All

Age

6 Years to 12 Years

Inclusion criteria

Inclusion criteria: Healthy children aged 6 to 12 without systemic disease Children with intact teeth, that are free from caries and enamel lesions and periodontal disease Children who have not taken any antibiotics in the last 4 weeks

Exclusion criteria

Exclusion criteria: Children with systemic diseases Children with decayed teeth or structural problems in the enamel Children who have taken antibiotics in the last four weeks

Design outcomes

Primary

Measure	Time frame
Saliva pH. Timepoint: Before using mouthwash, 5, 10, 15 and 20 minutes after using mouthwash. Method of measurement: Using digital pH meter.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehrnaz Mahmoodabadi

Shahid Beheshti University of Medical Sciences

Mahmoodabadimehrnaz@gmail.com+98 21 2243 9872

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026