With aging, there is an inevitable progressive loss of muscle mass and strength called sarcopenia that is associated with the risk of impairment in physical ability which could lead to consequences such as falls, fall-related injuries, hospitalizations, and even mortality.. Muscle wasting and atrophy, not elsewhere classified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age more than 65 years Handgrip strength lower than 32Kg SMM/height2 lower than 9.2 kg/m2 Being sedentary for at least 1 year (didn’t have more than 1h exercise per week)
Exclusion criteria
Exclusion criteria: Cardiovascular or pulmonary diseases, diabetes, Joint and muscle problems, and Mental and cognitive disorders Involvement in any extra exercise training programs Not interested to continue or change in personal life schedule
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Myostatin levels. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: Collection of venous blood samples with a syringe and laboratory assessments.;Follistatin levels. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: Collection of venous blood samples with a syringe and laboratory assessments.;GDF-15 levels. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: Collection of venous blood samples with a syringe and laboratory assessments.;CAF levels. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: Collection of venous blood samples with a syringe and laboratory assessments. | — |
Secondary
| Measure | Time frame |
|---|---|
| Handgrip strength. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: Jamar hand dynamometer (USA) with five handle positions and the second position was used for all participants.;Gait speed. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: Walking speed of participants was assessed using a stopwatch.;Time Up and Go (TUG). Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: TUG test was assessed using a stopwatch.;Chair stand speed. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: chair stand test was assessed using a stopwatch.;Standing balance. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: The standing balance test was assessed using a stopwatch. | — |
Countries
Iran (Islamic Republic of)
Contacts
Allameh Tabataba'i University