Investigating the effect of oral tizanidine on shoulder pain

Investigation of oral Tizanidine on postoperative shoulder pain in laparoscopic cholecystectomy compared to the control group

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230726058933N1

Enrollment

Registered

2023-09-05

Start date

2023-09-23

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shoulder pain after laparoscopic cystectomy.

Interventions

Intervention 1: Intervention group: 2 hours before general anesthesia for surgery, the patients will receive one dose of Tizanidine, prepared by Actoverco (Actoverco) under the brand name Tizanover, o

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients who undergo elective laparoscopic cholecystectomy surgery will be included in the study Patients must be between 18 and 65 years old

Exclusion criteria

Exclusion criteria: Patients whose surgery was changed from laparoscopy to laparotomy Patients who are allergic to tizanidine Patients who take opium

Design outcomes

Primary

Measure	Time frame
Shoulder pain. Timepoint: 2, 4 and 24 hours after surgery. Method of measurement: visual analogue scale.;Dose of painkillers received. Timepoint: With each injection in case of pain. Method of measurement: Number of injections.;Side effects of tizanidine. Timepoint: 2, 4 and 24 hours after surgery. Method of measurement: Ask the patient.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Beyzaii

Islamic Azad University

hmd_beyzaii@yahoo.com+98 51 3222 9094

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026