Comparison of Effect of ondansetron And Chlorpheniramine in controlling nausea in adults in emergency department

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230726058930N4

Enrollment

195

Registered

2024-05-11

Start date

2024-04-24

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nausea in emergency room patients.

Interventions

Intervention 1: Intervention group: In this group of patients, ondansetron is administered intravenously at a dose of 4 mg/2 ml. Intervention 2: Intervention group: This group of patients receives 4 m

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Satisfaction of patients to participate in the trial to be at least 18 years old The patient complains of nausea

Exclusion criteria

Exclusion criteria: trauma(specially abdomen) continuous vomiting which persists 1 hour after admission alcohol consumption unstable hemodynamic history of allergy to ondansetron or Chlorpheniramine pregnancy

Design outcomes

Primary

Measure	Time frame
The degree of change in the patient's nausea based on a scale from 1 to 10 in zero, 20 and 60 minutes. Timepoint: At the time of injection, 20 minutes and 60 minutes after. Method of measurement: Based on the visual analog scale questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Vefagh nematollahi

Ahvaz University of Medical Sciences

vefagh.a@ajums.ac.ir+98 61 3374 3099

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026