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Ibuprofen compared to ketorolac in improving renal colic pain

Evaluation of the effect of ibuprofen injection compared to ketorolac injection in improving renal colic pain of out patients after entering the emergency department

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230726058930N1
Enrollment
100
Registered
2023-10-18
Start date
2023-09-23
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal colic. Unspecified renal colic

Interventions

Intervention 1: Intervention group: The first group received a dose of 800 mg of intravenous ibuprofen in 250 cc of normal saline within 5 minutes to determine the pain intensity at 0, 20, 40, and 60

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients referred to the emergency center with acute renal colic pain caused by kidney stones Diagnosis of renal colic by an emergency medicine specialist considering clinical examination, urinalysis test (U/A), ultrasound based on the presence of mild and moderate hydronephrosis and rule out other differential diagnoses

Exclusion criteria

Exclusion criteria: Patients with coagulation disorders chronic kidney disease (CKD) severe hydronephrosis active gastrointestinal bleeding (GIB) patients who do not respond to treatment up to 30 minutes after drug injection patients who are candidates for surgical intervention patients with large stone size

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 0, 20, 40, 60 minutes after injection. Method of measurement: Numeric Pain Rating Scale (NRS).

Secondary

MeasureTime frame
Blood pressure. Timepoint: After injection of painkillers. Method of measurement: Blood pressure measuring device.;Shortness of breath. Timepoint: After injection of painkillers. Method of measurement: Borg shortness of breath scale.;Heart beat. Timepoint: After injection of painkillers. Method of measurement: Using a sphygmomanometer.;Nausea. Timepoint: After injection of painkillers. Method of measurement: Ask the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Vefagh nematollahi

Ahvaz University of Medical Sciences

vefagh.a@ajums.ac.ir+98 61 3374 3099

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026